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Interpreting Perturb-seq data remains challenging because single-cell RNA sequencing often misses transcripts from lowly expressed genes, producing zeros that can reflect either true knockdown or simple dropout. This ambiguity blurs the distinction between effective perturbations and escaped cells, making it difficult to assess gRNA performance, especially in large screens Read More

1. The Alignment/Registration Problem in Spatial Imaging In spatial imaging, researchers often analyze more than one representation of the same tissue. An H&E image provides structural context, while an IF image highlights specific markers. Many workflows even use a series of adjacent sections, where each section serves a different Read More

Astrocyte segmentation is challenging because these cells do not have simple shapes, are densely packed, and often intertwine with each other. Mapping them in brain images is notoriously difficult – signals blur, noise dominates, and current cell segmentation algorithms often fail, especially in injured tissues. Scientists at BioTuring Read More

1. The Target Identification Problem in IBD The core challenge in Inflammatory Bowel Disease (IBD) research is tissue heterogeneity. Inflammation affects different regions of the intestine and different cell types in distinct ways, making it difficult to interpret gene expression changes. Without knowing which cell type expresses a Read More

The Open Day is a community initiative jointly organized by BioTuring and the Vietnam Institute for Advanced Study in Mathematics (VIASM). Our mission is to help Vietnamese high school students explore the fascinating world of Bioinformatics – where data meets DNA, and science meets technology. Through exciting Read More

San Diego, CA & Boston, MA  The Human Cell Atlas (HCA) is a global, open consortium founded in 2016 with over 4,000 members across more than 100 countries, working to map every cell type in the human body and create a 3D Atlas to transform understanding of biology Read More

SAN DIEGO, CALIFORNIA – BioTuring has announced the launch of the new Talk2Data platform – a GPU accelerated multi-omics database built on NVIDIA Blackwell accelerated computing – enabling real-time analysis of over 500 million high-quality, expertly curated single cells across multiple omics layers. The platform offers an Read More

For Immediate Release LA JOLLA, CA—Scientists with ImmGenMaps are assembling a new kind of map: the first-ever complete cartography of the mouse immune system. The international team, which includes more than 50 scientists from 15 institutions, and is spearheaded by the Reina Lab Read More

In the fast-paced world of bioinformatics and pharmaceutical research, staying ahead means having the tools to unlock insights from vast datasets quickly and efficiently. Today, we’re thrilled to announce the launch of the new version of Talk2Data, a GPU-accelerated multi-omics database powered by NVIDIA Blackwell – enabling real-time analysis Read More

Given a spatial slide with cell type annotations, the goal is to identify regions with homogeneous cell type compositions. For example, with a slide containing two distinct cell types, we aim to identify regions such as: Region 1: only cell type A Region 2: composed of both Read More