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Transcriptional and cellular diversity of the human heart
Tucker, Nathan R and Chaffin, Mark and Fleming, Stephen Jordan and Hall, Amelia Weber and Parsons, Victoria A and Bedi, Kenneth and Akkad, Amer-Denis and Herndon, Caroline N and Arduini, Alessandro and Papangeli, Irinna and others
The human heart requires a complex ensemble of specialized cell types to perform its
essential function. A greater knowledge of the intricate cellular milieu of the heart is critical to increase
our understanding of cardiac homeostasis and pathology. As recent advances in low input RNAsequencing have allowed definitions of cellular transcriptomes at single cell resolution at scale, here we
have applied these approaches to assess the cellular and transcriptional diversity of the non-failing