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Transcriptional and cellular diversity of the human heart

Tucker, Nathan R and Chaffin, Mark and Fleming, Stephen Jordan and Hall, Amelia Weber and Parsons, Victoria A and Bedi, Kenneth and Akkad, Amer-Denis and Herndon, Caroline N and Arduini, Alessandro and Papangeli, Irinna and others

The human heart requires a complex ensemble of specialized cell types to perform its essential function. A greater knowledge of the intricate cellular milieu of the heart is critical to increase our understanding of cardiac homeostasis and pathology. As recent advances in low input RNAsequencing have allowed definitions of cellular transcriptomes at single cell resolution at scale, here we have applied these approaches to assess the cellular and transcriptional diversity of the non-failing human heart.

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Species: human
Number of cells: 287269
Number of downloads: 72
Study size: 2GB
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